The Twins signed Colon to a Minor League deal on July 7 after he was designated for assignment by Atlanta on June 29.
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As for why Colon will be starting on Tuesday, manager Paul Molitor said, "Some of it had to do with conversations that were made in bringing him over here and the timing of trying to get him in the rotation."
Colon gave up four runs on four hits with five strikeouts and two walks in 3 2/3 innings on Thursday in a Triple-A start for Rochester against Lehigh Valley.
With 235 Major League wins, Colon is nine shy of passing Juan Marichal as the winningest pitcher from the Dominican Republic.
Richard Dean is a contributor to MLB.com based in Houston and covered the Twins on Saturday. This story was not subject to the approval of Major League Baseball or its clubs.